A train and a school bus have collided near Perpignan in southern France, killing at least four children and injuring many others, some seriously, in the accident on a railway crossing between Millas and Saint-Féliu-d'Amont, reports BBC News.
The students on the bus are reported to be between the ages of 13 and 17.
Pictures from the scene showed the school bus sheared in two by the force of the crash.
Around 70 emergency workers and four helicopters were deployed as part of the rescue effort.
The crash happened on a section of line between Perpignan and Villefranche-de-Conflent, the local news website l'Indépendant reports.
A witness who was on the train, named as Barbara, said "it was a very violent crash - it seemed as if the train would derail".
Casualties were being taken to hospital in Perpignan. Rail travel is severely disrupted.
Transport minister Elisabeth Borne called the crash a "terrible accident" and said on Twitter that she was going to the scene, about 850km (530 miles) south of Paris. Prime Minister Edouard Philippe was also heading there.
Read more of this article, with video reporting, from BBC News.